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KMID : 0869120080100020184
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기초간호자연과학회지
2008 Volume.10 No. 2 p.184 ~ p.193
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Physiological Markers in Anxiety and Depression
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An Gyeong-Ju
Jeong Jae-Sim
Kim Yoon-Kyung
Jeong Hye-Sun
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Abstract
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Purpose: Anxiety and depression are the concepts that commonly used as an emotional approach in the nursing researches and most of researches have been used questionnaires as a marker of anxiety and depression. There were few researches using physiological markers in measuring anxiety and depression.
Methods: Journals published between 1950 and 2007 that include depression and anxiety measuring through physiological markers were reviewed.
Results: As in the case of the hypothlamus-pituitary-adrenal axis system, it appeared that cortisol, epinephrine, and norepinephrine belonged to the category of hormones which were responsive to anxiety and depression. Plasma norepinephrine was a marker of the anxiety whereas plasma cortisol was a marker of the depression. The anxiety and depression were correlated with immune and taste, but it considered as an outcome variable not a physiological marker.
Conclusion: Catecholamine and cortisol reflect anxiety and depression state. Our findings suggest that further researches are needed to distinguish between markers and outcomes of depression and anxiety using physiological markers.
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KEYWORD
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Anxiety, Depression, Physiological marker, Catecholamine, Cortisol
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